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From: Nikos Chantziaras <realnc@gmail.com>
Subject: [gentoo-user] Re: alsamixer - no sound
Date: Sun, 17 Dec 2023 05:00:48 +0200
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On 17/12/2023 01:54, thelma@sys-concept.com wrote:
> But the scary thing is I don't know what fix it and running as user: 
> alsamixer still does not allow me to save default sound card
> I select with F6.

You don't set a "default sound card" with F6. All that does is simply 
allow you to see the mixer controls of a different sound card.

You set your default sound card by using your desktop environment audio 
settings. In KDE, I click on the speaker tray icon and there I can 
select my default sound card and default microphone:

   https://i.imgur.com/Lz3Bfyk.png

Surely there's something similar in the desktop environment you're using.